Brand Names:

Zyloprim

What is it?

Allopurinol is a drug that is used to prevent gout attacks (or flares). It works by blocking the formation of uric acid, the substance responsible for causing these attacks when it is too high.

What’s In It For Me?

Gout can be very painful. Taking allopurinol on a daily basis will decrease the severity and number of attacks you have.

The Good

Allopurinol has been shown to be both safe and effective for the prevention of gout.

The Bad

It can take several months for you to see the full benefit of this medication. Like all medications, side effects are possible with allopurinol, although there is a very low rate. The most common side effects are skin reactions which occur in about 10%-15% of patients treated with this drug. Also, you may experience worsening gout if you start taking it in the middle of an attack.

The Controversial

Some investigators think that increased levels of uric acid may lead to a higher risk of heart disease. Allopurinol could reduce this risk by decreacing the formation of uric acid.

Fact Boxes

For The Cynic

Lifestyle modifications such as decreased alcohol use and weight loss can also help to decrease the number and severity of gout attacks.

The Cost

Allopurinol is very cheap. It can be found on the $4 list at some pharmacies.

Allopurinol is a very effective drug for preventing gout.  It is by far the drug of choice.

Written by:Chelsea Martinand edited by ProfJameson

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