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Insulin Dosing Rules

John and Albert in Bali Albert and I had to go into the beautiful mountains of the island of Bali to research these rules. Bali is one of many islands that make up the country of Indonesia. Somebody had to go.

Insulin Dosing Rules

Starting dose

0.5…

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Power Calculations

Statistical Power

OK, so John Lennon didn’t really write this , but statistical power is a very abstract concept and the ability to "imagine" really helps.

Overview

Power is the probability to detect a difference if it is there.

Of course, your next…

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Antibiotics Simplified

It might take a bit more than a minute, but we have created a powerpoint presentation that walks through most antibiotics and helps you see how one relates to another. This is a free resource for you called Antibiotics Oversimplified.…

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Warfarin Maintenance Dose Adjustments

Simple guidelines

Note: these are for maintenance doses only at steady state. Do NOT use these guidelines for starting someone on warfarin.

INR Dosage Adjustment
Less Than 1.3 Give them an extra dose and increase by 10% (always ask them if they “might” have missed…
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Millimoles and Millequivalents

Occasionally, you still need to figure out millequivalents vs millimoles. Or you may need to calculate how much sodium in half normal saline.

Two Pharm D. students prepared a powerpoint to easily walk you through these sometimes tricky calculations.

Millequivalents and…

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Ace Inhibitors and the Kidney

We have prepared a powerpoint to demonstrate how ACE inhibitors can be either beneficial or harmful to the kidney, depending on the patients physiology:

ACE INHIBITORS AND THE KIDNEY

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Number Needed to Treat

Definition:The Number Needed to treat is the number of patients that you would need to treat to prevent one primary outcome (heart attack, death, stroke, whatever)

  • This applies to patients: with the same problem studied
  • treated for the same duration as…
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Absolute vs Relative Risk Reduction

Albert and I developed an acute interest in risk reduction at about 3500 feet.

 

Examples:
Example 1A:

  • Consider the benefit of using Coumadin for Stroke prevention in Atrial Fibrillation. Moderate risk patients on placebo have 8% risk of stroke in ONE…
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Thyroid Pharmacotherapy

Normal Thyroid Physiology

Thyroid stimulation and feedback

Laboratory Tests for Thyroid

Total T4 Free T4 Total T3 TSH
Normal

4.5 - 12.5 mcg/dl

0.8 -  1.5 ng / dl

80 - 220 ng/dl

0.3 - µU /  mL

Hyperthyroid

Hypothyroid

Thyroid Clinical Pearls

  • Normal levothyroxine dose is 1.6 mcg/kg/ day
  • Some people may benefit symptomatically from addition of 50mcg…
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Beta Blocker Pharmacology

One Minute Genius

Beta Blocker Pharmacology

OK friends, to understand Beta Blocker Pharmacology:

#1 Learn the Fight or Flight Response
#2 Think opposite

Remember, Fight or Flight is the body system designed as an emergency response to help you fight an enemy or run away.…

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